Phytates & Calcium Absorption

Updated: May 12, 2023

Reviewed By:
Lara Pizzorno – AlgaeCal Scientific Advisory Board Member
MDiv, MA, LMT
Best-selling author of Healthy Bones Healthy You! and Your Bones; Editor of Longevity Medicine Review, and Senior Medical Editor for Integrative Medicine Advisors.

Many people are increasing their intake of plant-based protein these days, trading in some meat and dairy for bean and whole grain options and favoring a handful of nuts and seeds over snacks of highly processed chips, crackers, or cookies.  

While you know increasing your intake of legumes and whole grains is an excellent idea, you may have heard that phytates, potential “anti-nutrients” lurking in plant foods, will rob you of the minerals they contain. Should you be concerned? 

If you follow a vegan or vegetarian diet, maybe. Otherwise, no.

In this article, we’ll discuss phytates; what they are, where they are, what they do for your body, and how to best prepare your foods to get their benefits while also optimizing nutrient absorption.

And we’ll talk about a couple of minerals someone following a vegan or vegetarian diet may need to consume in greater amounts to ensure nutrient adequacy.  

What Are Phytates?

Phytates are compounds in plant foods that serve as a storage form of plant phosphate, an energy source for the plant, and as an antioxidant that enhances the plant’s defenses. 

The terms phytates and phytic acid are often used interchangeably, but they do refer to different compounds in plants. Phytic acid holds the potential to bind a mineral, while phytates have already bound one. In other words, phytic acid becomes a phytate once it has bound a mineral. 

Although phytates come with a host of benefits, they’re often considered “anti-nutrients” because of their ability to bind to minerals. This occurs because the phosphates that are components of phytates act as strong chelators or binding agents which have an affinity for positively charged minerals, like copper, calcium, zinc, and iron[1]. 

Phytates are present in a wide range of plant foods:

Foods High in Phytic Acid

  • Grains (wheat, rice, barley, sorghum, oat, rye, millet, triticale, wild rice)
  • Oil-containing seeds (sunflower kernels, sesame seeds, linseed, canola or rape seeds) and nuts (hazelnuts, walnuts, almonds, cashews, peanuts, Brazil nuts, pistachios, macadamia, pecans, pine nuts)
  • Legumes (beans [including soybeans and products made from them], peas, and lentils). 
  • Tubers (potatoes, beets, carrots, turnips)

What Do Phytates Do in The Body?

Phytates protect plants with their strong antioxidant defenses and also serve as a source of energy. Unsurprisingly, these beneficial plant effects also produce a wide range of positive effects in the human body.

For example[2][3][4][5]:

  • Phytates act as powerful antioxidants and provide significant anti-inflammatory effects. These plant compounds are even known to reduce the risk for certain cancers, including breast and colon cancer. 
  • Due to their anti-inflammatory activity, phytates may reduce the risk for inflammatory bowel disease. 
  • By protecting against inappropriate calcification, phytates prevent calcium from depositing in our blood vessels and lower our risk of developing kidney stones.
  • Phytates promote cardiovascular health, improving the overall lipid profile by increasing HDL, lowering oxidized LDL, and lowering triglycerides. 
  • Phytates assist in blood sugar control by reducing intestinal absorption of glucose and fat, while also increasing insulin sensitivity.
  • Due to their ability to stimulate the production of nitric oxide, phytates help relax blood vessels, improving blood flow and nutrient delivery throughout the body.
  • And finally, phytates bind to toxic minerals — e.g., lead, cadmium — preventing their absorption and escorting them out of the body via stool.

Phytates and Bone Health

Contrary to popular belief, phytates have a particularly beneficial impact on bone mineral health.

The positive impact of phytates on bone health comes from their ability to inhibit the breakdown of the calcium phosphate mineral complex in your bones called hydroxyapatite. This complex makes up approximately 65% of your bones and plays a crucial role in the structure and strength of your bones. 

Research shows that increased consumption of phytates is related to higher bone mineral density and, therefore, daily consumption of phytate-rich foods (at least one serving/day of legumes or nuts) may help to prevent or minimize bone-loss disorders, such as osteoporosis. [6]. 

Do Phytates Inhibit Calcium Absorption?

Phytic acid does, in fact, bind minerals such as calcium, zinc, magnesium, and iron. And while some animals produce the enzyme phytase, which allows the bound minerals to be liberated and absorbed, humans don’t. So, to answer the question, “Do phytates inhibit calcium absorption?” the simple answer would be “yes,” but the story isn’t so simple. 

While phytates do bind to calcium, research shows that people who consume a diet primarily consisting of plant foods don’t end up with the nutrient deficiencies you would expect from a phytate-rich diet[7][8].

How could this be?

A variety of factors likely play a role, including individual metabolism and cooking methods. While phytates are able to bind minerals, it appears that the overall amount of minerals bound by these “anti-nutrients” is not large enough to result in nutrient depletion. Furthermore, when foods that contain phytates are cooked, they lose a great deal of their phytic acid content, which means that even if a food is considered high in phytates, that may no longer be the case once the food is prepared. And who eats uncooked legumes or whole grains? 

All in all, studies show that when we consume a diverse and balanced diet, the likelihood of phytates impairing our mineral status is very low[1]. Those following a vegan or strict vegetarian diet are the one possible exception to this rule.

If organically grown, whole foods are chosen and prepared at home using the cooking techniques described next (presoaking, etc.), which both lower phytate content and improve mineral bioavailability, a vegan or vegetarian diet can provide excellent nutrition. However, because of the diet’s phytate content and its lack of animal-derived foods rich in bio-available iron and zinc, a vegan or vegetarian may need more than the RDA of these two minerals to prevent insufficiency[15].

To meet a vegan or vegetarian’s increased requirements, the IOM (Institute of Medicine) recommends:

  • Iron’s RDA should be multiplied by 1.8 
  • Zinc’s RDA should be multiplied by 1.5

Regarding iron, other experts in the field recommend simply enhancing non-heme (plant) iron absorption by consuming iron-rich plant foods along with vitamin C, and when eating iron-rich meals, reducing consumption of other dietary inhibitors of iron absorption, i.e., the tannins found in tea, coffee and cocoa. Enjoy your tea, coffee or cocoa an hour or so before or after your iron-rich meal.  

Zinc, however, is a special case due to its already poor bioavailability. Vegans should frequently consume zinc-rich foods such as hemp, pumpkin seeds, nutritional yeast, oats and other grains, nuts and beans, and use the cooking methods described next that improve mineral absorption. Even so, if 12 mg/d cannot be easily provided by your diet, supplemental zinc may be a wise option. 

How to Reduce Phytic Acid in Food

Phytates can easily be reduced through food preparation and cooking processes, including fermentation, soaking, and germination. Once your phytate-rich foods have undergone these processes, their phytate content and ability to bind minerals will be significantly reduced, enhancing the nutrient absorption of your meal[9].  

Fermentation

Fermentation involving lactic acid bacteria can lower the phytate level in grains between 12-51%, depending on the type of grain. Furthermore, studies show that consuming fermented vegetables along with high-phytate foods can also increase mineral absorption by lowering overall active phytate levels[10][11].

Cooking

Cooking your foods will also degrade some of the phytic acid content. For example, studies show that cooking legumes for one hour at 95 °C results in somewhere between a 23% and 80% loss in phytic acid[12].

Soaking

Soaking seeds and legumes is a common practice for enhancing nutrient bioavailability and is the easiest way to go about it. Soaking foods in fresh water for 24 hours, then draining and replacing with fresh water before cooking, can reduce phytate levels by up to 23%, after which cooking will lower them even more.

While soaking may also result in a slight loss of iron and zinc,[13], it’s easy to not just replenish but increase the content of both when cooking the soaked seed or legume. Simply add a teaspoon of ascorbic acid (vitamin C) and a piece of dried kombu (seaweed) to your cooking water. Kombu is loaded with minerals, which will then be absorbed by the seed or legume while cooking. Vitamin C, specifically, boosts the absorption of nonheme iron (Fe3+, the form in which iron is found in plant foods) by donating an electron and reducing it to Fe2+, which is the only form in which iron can be absorbed by our enterocyte cells (the absorptive cells that line the inner surface of our small and large intestines)[16]. 

Germination

Germination or sprouting can also enhance plant foods’ nutrient bioavailability by activating phytases (enzymes) within the foods that then liberate phosphates from the phytate complex and therefore put an end to its mineral-binding properties. Sprouting is a particularly helpful way to preserve the mineral content of your food[14]. 

Takeaway

While it’s true that phytic acid may bind some minerals, including calcium, this “anti-nutrient” is truly anything but. Phytate not only enhances your antioxidant defenses and lowers inflammation but can enhance your bone health and help prevent bone diseases like osteoporosis. 

If you’re worried about the phytate content of your meals, keep in mind that the way you prepare and cook phytate-containing foods can significantly reduce their phytic acid content, render the nutrients they contain more bioavailable and even enrich the mineral content of the cooked food.   

For more tips about bone health and aging well, sign up for the AlgaeCal Newsletter, where you’ll receive the latest news and research to guide your healthy living practices. 

FAQs

What do phytates do in your body?

Phytates act as antioxidants, protect against calcification (where it doesn’t belong), are anti-inflammatory, bind toxic metals, stimulate the production of nitric oxide, assist in blood sugar regulation, and protect bone and cardiovascular health. 

Are phytates harmful?

While phytates can bind to minerals like calcium, for most people they don’t bind enough to produce a mineral deficiency. Those following a vegan or strict vegetarian diet are the one possible exception to this rule. Due to the diet’s phytate content and its lack of animal-derived foods rich in bio-available iron and zinc, a vegan or strict vegetarian may need more than the RDA of these two minerals to prevent insufficiency.

What foods are high in phytates?

Phytates are found in a range of plant foods. Some of the plants with the highest levels of phytates include grains (like wheat, rice, and barley), legumes (including beans, peas, and lentils), nuts, seeds, and tubers (such as potatoes, beets, and carrots). 

How do you get rid of phytates?

You can reduce phytates in your food through various preparation methods, including fermentation, cooking, soaking, and germination. You can also find some legumes and grains pre-sprouted, which will naturally reduce their phytate content. 

References

  1. Petroski, Weston, and Deanna M. Minich. “Is there such a thing as “anti-nutrients”? A narrative review of perceived problematic plant compounds.” Nutrients 12.10 (2020): 2929.
  2. Cohen, L. A. “Dietary fiber and breast cancer.” Anticancer research 19.5A (1999): 3685-3688.
  3. Fuster, Juan Manuel Buades, et al. “Plant phosphates, phytate and pathological calcifications in chronic kidney disease.” Nefrología (English Edition) 37.1 (2017): 20-28.
  4. de Melo Ribeiro, Priscila Vaz, et al. “Dietary non-nutrients in the prevention of non-communicable diseases: Potentially related mechanisms.” Nutrition 66 (2019): 22-28.
  5. Schlemmer, Ulrich, et al. “Phytate in foods and significance for humans: food sources, intake, processing, bioavailability, protective role and analysis.” Molecular nutrition & food research 53.S2 (2009)
  6. Sanchis, Pilar, et al. “Understanding the Protective Effect of Phytate in Bone Decalcification Related-Diseases.” Nutrients 13.8 (2021): 2859.
  7. Gibson, Rosalind S. “Content and bioavailability of trace elements in vegetarian diets.” The American journal of clinical nutrition 59.5 (1994): 1223S-1232S.
  8. Hunt, Janet R. “Moving toward a plant-based diet: are iron and zinc at risk?.” Nutrition reviews 60.5 (2002): 127-134.
  9. Gupta, Raj Kishor, Shivraj Singh Gangoliya, and Nand Kumar Singh. “Reduction of phytic acid and enhancement of bioavailable micronutrients in food grains.” Journal of food science and technology 52.2 (2015): 676-684.
  10. Castro‐Alba, Vanesa, et al. “Fermentation of pseudocereals quinoa, canihua, and amaranth to improve mineral accessibility through degradation of phytate.” Journal of the Science of Food and Agriculture 99.11 (2019): 5239-5248.
  11. Scheers, Nathalie, et al. “Increased iron bioavailability from lactic-fermented vegetables is likely an effect of promoting the formation of ferric iron (Fe3+).” European journal of nutrition 55.1 (2016): 373-382.
  12. Shi, Lan, Susan D. Arntfield, and Michael Nickerson. “Changes in levels of phytic acid, lectins and oxalates during soaking and cooking of Canadian pulses.” Food Research International 107 (2018): 660-668.
  13. Lestienne, Isabelle, et al. “Effects of soaking whole cereal and legume seeds on iron, zinc and phytate contents.” Food chemistry 89.3 (2005): 421-425.
  14. Duhan, A., N. Khetarpaul, and S. Bishnoi. “Changes in phytates and HCl extractability of calcium, phosphorus, and iron of soaked, dehulled, cooked, and sprouted pigeon pea cultivar (UPAS-120).” Plant Foods for Human Nutrition 57.3 (2002): 275-284.
  15. Rogerson, David. “Vegan diets: practical advice for athletes and exercisers.” Journal of the International Society of Sports Nutrition 14.1 (2017): 36.
  16. Piskin, Elif, et al. “Iron absorption: factors, limitations, and improvement methods.” ACS omega 7.24 (2022): 20441-20456.

Article Comments

Add New Comment

Your email address will not be published. Required fields are marked *

  1. Jodi Dann

    February 19, 2023 , 8:09 am

    I enjoyed this article, but not being a scientist or nutritionist I found this information about phytates to be confusing and contradicting.

  2. Manja

    February 22, 2023 , 12:08 pm

    I’m sorry you found the article confusing, Jodi! Please let us know if there’s anything we can further clarify for you. The main takeaway of the article is that you should not worry too much about phytates in your food unless you’re vegan or vegetarian. Even then, phytates can easily be reduced through food preparation and cooking processes, including fermentation, soaking, and germination. Let us know if you have any questions!

    – Manja @ AlgaeCal

  3. lynn

    June 15, 2023 , 6:52 am

    Hi. I’m taking algaecal… but i’m confused by the article as well. can you please email me exactly what I (we) can eat? Like–can i buy a can of white beans at the supermarket and eat those as a source of phytates? (what brand?), etc.
    thanks, lynn

  4. Samantha AlgaeCal

    June 15, 2023 , 12:05 pm

    Lynn, we apologize for any confusion caused by this article you read! Phytates have antioxidant properties and are beneficial for consumption, but they can bind to minerals like calcium, reducing their absorption. To optimize the absorption of foods rich in phytates, it’s essential to cook, ferment, soak, or germinate them. By following these cooking techniques, the phytic acid that binds to minerals will decrease, and the nutrient absorption of your meals will improve. Therefore, you can enjoy a can of white beans without worry. We hope this information clears things up for you. If you have any further questions, please don’t hesitate to ask. 🙂

    – Sam @ AlgaeCal

  5. Jan Cox

    February 22, 2023 , 5:22 am

    I am confused- in the first FAQ it is stated all the positive impact on our bodies. But that last FAQ talks about getting RID of phylates in our body. I thought we wanted them.

    I eat plant base 60-80% of my diet.

    Please help me understand.

    thanks 🙂

  6. Manja

    February 22, 2023 , 12:19 pm

    Thank you for reaching out, Jan! As the article suggests, phytates produce a wide range of positive effects in the human body. But just like with many other foods, they should be consumed in moderation. All in all, studies show that when we consume a diverse and balanced diet, the likelihood of phytates impairing our mineral status is very low. Those following a vegan or strict vegetarian diet are the one possible exception to this rule. If this is true for you, you can then follow the suggestions provided at the end of the article to reduce phytic acid in your foods. Otherwise, you should not be overly concerned. Should you have any more questions, don’t hesitate!

    – Manja @ AlgaeCal

  7. Laura

    February 22, 2023 , 7:20 am

    I eat one sweet potato with my lunch every day but I thought your article was confusing
    Walked away wondering am I doing the right thing or not???

  8. Manja

    February 22, 2023 , 12:32 pm

    Hi Laura! Provided that you’re eating a diverse and well-balanced diet throughout the day, you do not have to question if you’re doing the right thing. Even if you follow a vegan or strict vegetarian diet where you would potentially be consuming lots of foods high in phytates, you can reduce the amounts of phytic acid content through different food preparation and cooking processes explained in the article. If you’re interested, we have a lot of helpful information geared towards bone health and nutrition over on our BLOG. Let us know if you have any questions!

    – Manja @ AlgaeCal

  9. Lizabeth

    February 23, 2023 , 1:17 am

    Extremely informative! We consume a well-balanced diet (inc fish protein) and enjoy many foods rich in phytates. So glad they’re good for me and my bones because we love our potatoes, beets, carrots, almonds and rice! Thanks 🙂

  10. Chelsea Dugas

    February 23, 2023 , 11:47 am

    Happy to hear it, Lizabeth! It’s all about balance in the end. Keep enjoying those foods you love! 🙂

    – Chelsea @ AlgaeCal

  11. Joan

    February 22, 2023 , 12:14 pm

    Very interesting article. Where it says to add ascorbic acid and kombu to the cooking water for legumes, etc., wouldn’t the vitamin C be destroyed by the heat of the cooking water?

  12. Chelsea Dugas

    February 28, 2023 , 7:39 am

    Such a great question, Joan! Some studies have shown that depending on the method of cooking used, loss of vitamin C can range from 15 to 55 percent. So yes, some vitamin C will be lost, but there is still some left to assist in the absorption of nonheme iron! You can also add a splash of fresh lemon juice to your food when eating or to a glass of water to boost that vitamin C even further! Hope this helps to clarify! 🙂

    – Chelsea @ AlgaeCal

  13. Anthony Boyle

    February 22, 2023 , 3:28 pm

    Now I’m more confused than I was when I started this chapter in my life

  14. Chelsea Dugas

    February 23, 2023 , 11:58 am

    Hi, Anthony!

    Could you please specify what part of the article was confusing to you?

    – Chelsea @ AlgaeCal

  15. Marlene Cohen Adair

    February 22, 2023 , 9:32 pm

    Great educational material. Thanks so much. It’s news I can use

  16. Chelsea Dugas

    February 23, 2023 , 11:56 am

    Very happy to hear this, Marlene! 🙂

    – Chelsea @ AlgaeCal

  17. Loren Fishman

    February 23, 2023 , 6:28 am

    Excellent Article. Thank you

  18. Kathleen Minahan

    February 23, 2023 , 6:46 am

    I thought this article was very confusing

  19. Chelsea Dugas

    February 23, 2023 , 12:21 pm

    Sorry to hear that, Kathleen. Could you please specify which part you found confusing?

    – Chelsea @ AlgaeCal

  20. Bobbie Evans

    February 23, 2023 , 12:09 pm

    PLEASE send me the recipe for the first picture in this article with the beef and sweet potatoes. Yummy

  21. Chelsea Dugas

    February 28, 2023 , 5:59 am

    Hi, Bobbie! I’m so sorry, that doesn’t seem to be one of our recipes, but perhaps you’d be interested in our Protein-Packed Braised Boneless Beef Short Ribs! Hope this helps! 🙂

    – Chelsea @ AlgaeCal

  22. Suzanne Zandrew

    February 23, 2023 , 1:04 pm

    Great information. Thank you

  23. Malva Bee

    February 28, 2023 , 5:07 pm

    A lot of contradiction in this article! Disappointed!

  24. Manja

    March 1, 2023 , 9:36 am

    Please let us know if there are any particular concerns we can clarify for you, Malva. We understand the information can be quite overwhelming. The main takeaway of the article is that you should not worry too much about phytates in your food unless you’re vegan or vegetarian. Even then, phytates can easily be reduced through food preparation and cooking processes explained in the article.

    – Manja @ AlgaeCal

  25. Caryn Milano

    July 3, 2023 , 5:19 am

    It was great hearing about all this information about our bones etc. to kept us healthy and strong, as we age gracefully.

  26. Brianne AlgaeCal

    July 3, 2023 , 8:26 am

    We’re so happy that you found this information helpful, Caryn! 🙂

    – Brianne @ AlgaeCal

  27. Robin Weiler

    November 22, 2023 , 4:57 pm

    Hello,

    Do phytates also bind the calcium in marine algae calcium supplements?

    Thank you, Robin

  28. Yoori AlgaeCal

    November 23, 2023 , 4:05 pm

    Great question, Robin! While phytates are known to bind to minerals, my understanding is that the interaction between phytates and calcium from marine algae supplements can vary depending on the source. We recommend verifying this information with a healthcare professional :).

    – Yoori

This article features advice based on cutting-edge research from our industry experts to give you the best possible information to support your bone-building journey.

Lara Pizzorno
MDiv, MA, LMT - Best-selling author of Healthy Bones Healthy You! and Your Bones; Editor of Longevity Medicine Review, and Senior Medical Editor for Integrative Medicine Advisors.,
Dr. Liz Lipski
PhD, CNS, FACN, IFMP, BCHN, LDN - Professor and Director of Academic Development, Nutrition programs in Clinical Nutrition at Maryland University of Integrative Health.,
Dr. Emma Gasinski
PT, DPT, RYT - Physical therapist and certified yoga teacher with a Doctorate in Physical Therapy from Rocky Mountain University of Health Professionals,
Dr. Lawrence (Larry) A. May
MD, FACP, Harvard Medical School Graduate, Physician, Author, Public Speaker - Doctor of Internal Medicine at Providence Cedars-Sinai Tarzana Medical Center and author of several articles and books, including the widely utilized and best selling medical textbook Primary Care Medicine,